Notice! Beware of "ototoxicity" in children's chemotherapy drugs

time:2022-12-09 01:18:04source´╝Ümonlittlebaby.com author:Diet
Notice! Beware of "ototoxicity" in children's chemotherapy drugs

*For medical professionals to read for reference only. As one of the most commonly used drugs in combination chemotherapy, cisplatin has curative effect on a variety of solid tumors, but its nephrotoxicity rate is high. Therefore, during chemotherapy and A lot of hydration is required after finishing. It is also important to pay attention to the therapeutic dose, so how should cisplatin be used in children? What should I pay attention to? Let's learn together! How to treat multiple solid tumors? When cisplatin is used to treat a variety of solid tumors, the recommended dosage is as follows: 1. As a monotherapy, the usual dose for children is 50-100mg/m2, intravenously once every 3-4 weeks, or 15-20mg/day intravenously. 2. If combined with chemotherapy, the recommended dose is 20 mg/m2 or higher, once every 3-4 weeks, but the dose of cisplatin alone cannot be exceeded. In addition, according to the child's weight, cisplatin should be diluted and instilled with an appropriate amount of sodium chloride injection. FDA: Caution Ototoxicity Ototoxicity may be more severe in pediatric patients receiving cisplatin injection, especially those younger than 5 years, with an estimated prevalence of hearing loss of 40%-60% in pediatric patients. The FDA recommends testing of hearing and vestibular function in all pediatric patients receiving cisplatin because early detection of hearing impairment can limit its potential impact on the cognitive and social development of pediatric patients. More Corey's popular drugs, where to learn? Pediatric medication is no trivial matter. Some medicines do not have corresponding dosage forms for children. Can children use them? Do I need to adjust the dose? Polyene phosphatamide contains benzyl alcohol, children are prohibited! The Food and Drug Administration warns infants and young children under the age of 2 to use paracetamol with caution... What other drugs are banned for children? The "Pediatric Drugs" column of the dry medicine doctor station you want is all available­čĹç1. Scan the QR code below 2. Click "Download Now" 3. Open the Doctor Station App and click the column 4. Find "evidence-based medicine" in the clinical medication Pay attention to the column and subscribe to the column, and read the hot drug search every day! Download the Doctor Station App and subscribe anytime, anywhere~
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