What are the uses of "Mannitol"? What to do with overdose? One article answer

time:2022-10-07 13:26:38source:monlittlebaby.com author:Common phenomenon
What are the uses of "Mannitol"? What to do with overdose? One article answer

For medical professionals' reading and reference only, learn a hot search drug every day. Mannitol injection can be used to treat diseases such as cerebral edema, intracranial hypertension and glaucoma. Then, according to the purpose of its clinical application, how to determine the dosage for children? How to deal with overdose? Let's learn together! 4 major clinical applications 1. Diuretic treatment: according to the child's body weight 0.25g/kg or according to the body surface area 60g/m2 administration, with 15%-20% solution intravenous drip within 2-6h. 2. Treatment of cerebral edema, intracranial hypertension and glaucoma: according to the child's weight 1-2g/kg or according to the body surface area 30-60g/m2, 15%-20% concentration solution is intravenously infused within 30-60min. The dose is reduced to 0.5g/kg when the child is frail. 3. Differentiate between prerenal oliguria and renal oliguria: according to the child's weight 0.2g/kg or according to the body surface area 6g/m2, intravenous infusion at a concentration of 15%-25% for 3-5min, such as 2- If the urine volume of children does not increase significantly in 3 hours, it can be used again. If there is still no reaction, it will not be used again. 4. Treatment of drug and poison poisoning: according to the child's weight 2g/kg or according to the body surface area 60g/m2: according to the child's weight 2g/kg or according to the body surface area 60g/m2 administration, with 5%-10% solution intravenous drip. How to deal with drug overdose? ▌Overdose Overdose can cause symptoms such as renal failure and AKI, hypovolemia/hypervolemia, hyperosmolarity and electrolyte imbalance, central nervous system toxicity (eg, coma, seizures). ▌Solution
  • Stop the infusion and take appropriate corrective action, paying particular attention to renal, cardiac and pulmonary system reactions.
  • Corrects fluid and electrolyte imbalances.
  • Mannitol solutions are dialyzable (hemodialysis and peritoneal dialysis), and hemodialysis may increase the elimination of mannitol solutions.
Where can I learn more popular medicines from Corey? Pediatric medication is no trivial matter. Some medicines do not have corresponding dosage forms for children. Can children use them? Do I need to adjust the dose? Polyene phosphatamide contains benzyl alcohol, children are prohibited! The Food and Drug Administration warns infants and young children under the age of 2 to use paracetamol with caution... What other drugs are banned for children? The "Pediatric Drugs" column of the dry medicine doctor station you want is all available👇1. Scan the QR code below 2. Click "Download Now" 3. Open the Doctor Station App and click the column 4. Find "evidence-based medicine" in the clinical medication Pay attention to the column and subscribe to the column, and read the hot drug search every day! Download the Doctor Station App and subscribe anytime, anywhere~
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